Abstract Title:

Grape Stem Extracts From Three Native Greek Vine Varieties Exhibit Strong Antioxidant and Antimutagenic Properties.

Abstract Source:

Anticancer Res. 2020 Apr ;40(4):2025-2032. PMID: 32234893

Abstract Author(s):

Aristidis S Veskoukis, Eleni Vassi, Konstantinos Poulas, Manolis Kokkinakis, Eftihia Asprodini, Serkos Haroutounian, Demetrios Kouretas

Article Affiliation:

Aristidis S Veskoukis


BACKGROUND/AIM: The winemaking procedure results in the generation of stems, a by-product that is harmful to the environment. Concomitantly, stems are rich in polyphenols and, hence, they are putatively beneficial for human health.

MATERIALS AND METHODS: In this study, the grape stem extracts derived from three native Greek vine varieties, namely Mavrodaphne, Muscat and Rhoditis were examined for their chemical composition and antioxidant and antimutagenic properties using a battery of in vitro biomarkers.

RESULTS: All extracts are rich in polyphenols. Moreover, they exhibit potent antioxidant and antimutagenic properties with the extract of Mavrodaphne being the strongest in reducing the DPPHand Oradicals and the Feand in protecting plasmid DNA from peroxyl radical-induced oxidative modification.

CONCLUSION: Therefore, although they are serious pollutants, grape stems contain phytochemicals with important biological properties and can be used as (ingredients of) bio-functional foods to improve certain aspects of human health.

Study Type : In Vitro Study

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