Guillain-barré syndrome variant occurring after SARS-CoV-2 vaccination. - GreenMedInfo Summary
Guillain-Barré Syndrome Variant Occurring after SARS-CoV-2 Vaccination.
Ann Neurol. 2021 08 ;90(2):315-318. Epub 2021 Jul 2. PMID: 34114269
Christopher Martin Allen
Although SARS-CoV-2 vaccines are very safe, we report 4 cases of the bifacial weakness with paresthesias variant of Guillain-Barré syndrome (GBS) occurring within 3 weeks of vaccination with the Oxford-AstraZeneca SARS-CoV-2 vaccine. This rare neurological syndrome has previously been reported in association with SARS-CoV-2 infection itself. Our cases were given either intravenous immunoglobulin, oral steroids, or no treatment. We suggest vigilance for cases of bifacial weakness with paresthesias variant GBS following vaccination for SARS-CoV-2 and that postvaccination surveillance programs ensure robust data capture of this outcome, to assess for causality. ANN NEUROL 2021;90:315-318.