Hepatoprotective phenylethanoid glycosides from Cirsium setosum. - GreenMedInfo Summary
Hepatoprotective phenylethanoid glycosides from Cirsium setosum.
Nat Prod Res. 2016 Aug ;30(16):1824-9. Epub 2015 Sep 11. PMID: 26358803
Qinge Ma
Two new phenylethanoid glycosides, namelyβ-D-glucopyranoside, 1″-O-(7S)-7-(3-methoxyl-4-hydroxyphenyl)-7-methoxyethyl-3″-α-L-rhamnopyranosyl-4″-[(8E)-7-(3-methoxyl-4-hydroxyphenyl)-8-propenoate] (1) and β-D-glucopyranoside, 1″-O-(7S)-7-(3-methoxyl-4-hydroxyphenyl)-7-methoxyethyl-3″-α-L-rhamnopyranosyl-4″-[(8E)-7-(4-hydroxyphenyl)-8-propenoate] (2), together with six phenylethanoid glycosides were isolated from Cirsium setosum. Their structures were elucidated by their spectroscopic data and references. Compounds 2, 4, 5, 7 and 8 (10 μM) exhibited moderate hepatoprotective activities. Compounds (3-8) were obtained from this plant for the first time.