Abstract Title:

Red Meat Consumption and the Risk of Stroke: A Dose-Response Meta-analysis of Prospective Cohort Studies.

Abstract Source:

J Stroke Cerebrovasc Dis. 2016 May ;25(5):1177-86. Epub 2016 Feb 27. PMID: 26935118

Abstract Author(s):

Cuili Yang, Lei Pan, Chengcao Sun, Yongyong Xi, Liang Wang, Dejia Li

Article Affiliation:

Cuili Yang


BACKGROUND: Prospective studies of red meat consumption and risk of stroke have provided inconsistent results. We aimed to assess this association by conducting a meta-analysis of prospective cohort studies.

METHODS: Relevant studies were identified by searching PubMed and EMBASE through April 1, 2013. Summary relative risks (RR) and the corresponding 95% confidence intervals (CIs) were estimated by random-effect or fixed-effect models.

RESULTS: Seven prospective cohort studies were included in the analyses, involving 2,079,236 subjects and 21,730 strokes cases. Total red meat consumption was associated with total stroke (RR = 1.14, 95% CI 1.05-1.24), cerebral infarction (RR = 1.13, 95% CI 1.0-1.28), and ischemic stroke (RR = 1.22, 95% CI 1.01-1.46). A significant association was found between consumption of processed red meat and total stroke (RR = 1.17, 95% CI 1.09-1.27). Consumption of fresh red meatwas significantly associated with total stroke (RR = 1.13, 95% CI 1.04-1.22) and ischemic stroke (RR = 1.15, 95% CI 1.03-1.29). However, no evidence suggests that any type of meat was associated with hemorrhagic stroke. Also, no association was found between consumption of processed red meat and ischemic stroke (RR = 1.15, 95% CI .98-1.36) and between consumption of fresh red meat and cerebral infarction (RR = 1.06, 95% CI [.94, 1.20]). A significant risk for total stroke could be observed when the consumption of total red meat was above 50 g/day, processed red meat was justabove 0 g/day, and fresh red meat was above 70 g/day.

CONCLUSION: Our findings indicate that high consumption of red meat, especially processed red meat, will increase the risk of stroke.

Study Type : Meta Analysis
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Problem Substances : Meat : CK(581) : AC(52)

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