Article Publish Status: FREE
Abstract Title:

[Vitamin D intake in young children with acute lower respiratory infection].

Abstract Source:

Zhongguo Dang Dai Er Ke Za Zhi. 2012 Jan ;14(1):1-6. PMID: 22289742

Abstract Author(s):

Karen S Leis, J Dayre McNally, Matthew R Montgomery, Koravangattu Sankaran, Chandima Karunanayake, Alan M Rosenberg

Article Affiliation:

Karen S Leis


OBJECTIVE: To determine if vitamin D intake is associated with acute lower respiratory infections (ALRI) in children.

METHODS: The vitamin D intakes of children younger than 5 years of age admitted to hospital with either bronchiolitis or pneumonia were compared to an unmatched control group of the same age without respiratory infection. Caregivers of 197 children completed a questionnaire collecting information on demographic variables, ALRI risk factors and diet. Associations of ALRI with vitamin D intake and other ALRI risk factors were determined.

RESULTS: The mean vitamin D intake of children with ALRI was 48 IU/kg/d compared to 60 IU/kg/d in the control group. When controlling for age, ethnicity, socio-economic status, northern residence, breastfeeding, immunizations and smoking contact, children with a vitamin D intake of less than 80 IU/kg/d were greater than 4 times more likely to have ALRI compared to children with a vitamin D intake exceeding 80 IU/kg/d (OR=4.9; 95%CI: 1.5-16.4).

CONCLUSIONS: A higher vitamin D intake than currently recommended might be needed to offer protection against diseases such as ALRI. Increased vitamin D supplementation could have important public health consequences, as bronchiolitis and pneumonia are the most common reasons for hospitalization in young children. (Full English version will be available online at www.amepc.org/tp.).

Study Type : Human Study

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