Hydrogel film loaded with new formula from Manuka honey for treatment of chronic wound infections.
J Glob Antimicrob Resist. 2017 Aug 19. Epub 2017 Aug 19. PMID: 28830809
Fady F Abd El-Malek
OBJECTIVE: Chronic wound infections can be effectively treated using hydrogel loaded with an extract from Manuka honey.
METHODS: This study was performed on bacterial isolates, isolated from patients having infected wounds at Alexandria Main University Hospitals, Egypt. Isolates were exposed to hydrogel sheets composed of chitosan and gelatin and loaded with new formula from Manuka honey.
RESULTS: Results illustrate the antibacterial activity of the formula extracted from Manuka honey against S. aureus, S. pyogenes, A. baumannii, P. aeruginosa and P. mirabilis. Screening of the Hydrogel using Electron Microscope shows the ultrastructure of the gel.
CONCLUSION: A hydrogel sheet composed of chitosan and gelatin loaded with the formula extracted from Manuka honey can be used as a dressing for chronic infected wounds.