Abstract Title:

Hydrogenated oil decreases tissue concentrations of n-6 polyunsaturated fatty acids and may contribute to dyschondroplasia in broilers.

Abstract Source:

Br Poult Sci. 1991 Dec;32(5):1109-19. PMID: 1786572

Abstract Author(s):

B A Watkins, C C Whitehead, S R Duff

Article Affiliation:

Purdue University, Department of Food Science, West Lafayette, IN 47907.


1. In a factorial design of dietary treatments, male Ross broilers were given diets containing soyabean oil, hydrogenated soyabean oil (as a source of trans-fatty acids) or feed fat with either 0 or 300 micrograms of added D-biotin/kg. 2. Growth to 28 d was not influenced by the dietary treatments. 3. Length of tibiotarsal bones was reduced (P less than 0.05) and severity of leg bone cartilage lesions, characteristic of dyschondroplasia, was highest (P less than 0.05) in broilers fed on diets containing hydrogenated soyabean oil. 4. Feeding hydrogenated soyabean oil lowered (P less than 0.05) the concentrations of C20:4n6 and the ratios of C20:4n6/C18:2n6 in liver and growth plate cartilage. 5. Growth plate cartilage from birds affected with dyschondroplasia contained lower proportions of prostaglandin precursor fatty acids compared with normal growth plate. 6. It is speculated that an inhibition of prostaglandin biosynthesis brought about by the presence of trans-fatty acids might contribute to the occurrence of lesions similar to dyschondroplasia.

Study Type : Animal Study
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