Abstract Title:

Hypoglycemic effect of rosmarinic acid-rich infusion (RosCE) fromin alloxan-induced diabetic rats.

Abstract Source:

Nat Prod Res. 2021 Oct 14:1-7. Epub 2021 Oct 14. PMID: 34647501

Abstract Author(s):

Márcio L A E Silva, Rodrigo Lucarini, Fransergio F Dos Santos, Carlos H G Martins, Patricia M Pauletti, Ana H Januario, Mario Ferreira Conceição Santos, Wilson R Cunha

Article Affiliation:

Márcio L A E Silva


known for its medicinal value, is officially accepted in many countries. The flowers and leaves are used globally in homeopathy. In Brazilian folk medicine,has been used to treat diabetes mellitus. This study evaluated the hypoglycemic activity of an infusion extract (RosCE) of commercially availableleaves in alloxan-induced diabetic rats. Oral administration of RosCE resulted in the reduction of blood glucose levels after the first day of treatment, compared to the diabetic control group. These results showed that RosCE displays hypoglycemic activity, which may be due to the combined effect of rosmarinic acid, and other minor compounds. Reversed phase-high performance liquid chromatography-diode array detection was used to identify and quantify the major constituents of RosCE. This study presents evidence that supports the folkloric use offor the treatment of hyperglycemia, confirming the use of its infusion as an antidiabetic herbal medicine.

Study Type : Animal Study

Print Options

Key Research Topics

Sayer Ji
Founder of GreenMedInfo.com

Subscribe to our informative Newsletter & get Nature's Evidence-Based Pharmacy

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.

Download Now

500+ pages of Natural Medicine Alternatives and Information.

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2022 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.