The impact of Vipassana meditation on health and well-being. - GreenMedInfo Summary

Vipassana meditation, an ancient Buddhist-derived practice that emphasises insight through non-judgmental observation of sensations and thoughts, has gained popularity for its potential to enhance health and well-being. Building on earlier research, this updated review synthesises empirical evidence published since 2010 to evaluate the impact of Vipassana across the psychological, physiological, neurobiological, and behavioural domains, addressing the growing need for effective, evidence-based approaches to global mental health challenges. Following the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines, databases such as PubMed, Cochrane Library, Google Scholar, PsycINFO, and Scopus were searched from January 2010 to April 2025 to identify relevant studies. Eligible studies comprised randomized controlled trials (RCTs), single-arm trials, pilot studies, and observational designs published in English, involving adult participants and quantifiable outcomes. Reviews, non-Vipassana practices, and low-quality studies with fewer than 10 participants per group were excluded, while the risk of bias was assessed using the Cochrane Risk of Bias (RoB) 2 tool and Newcastle-Ottawa Scale. Given the heterogeneity, the findings were synthesised narratively, exploring subgroups based on retreat intensity and practitioner experience. Eleven studies were included (three RCTs, two single-arm trials, one pilot trial, and five observational trials), revealing psychological outcomes such as reductions in stress and anxiety alongside gains in mindfulness and well-being; physiological and neurobiological findings included improved hippocampal topology, increased heart rate variability, and fewer migraine days; and behavioural improvements encompassed enhanced executive functions and memory consolidation, with stronger effects noted in intensive retreats and among experienced meditators, although evidence was limited by small sample sizes, moderate to high risk of bias, and absence of blinding. In conclusion, moderate evidence supports the benefits of Vipassana meditation for psychological and physiological health, particularly in alleviating stress, anxiety, and migraine burden while enhancing mindfulness and neurobiological markers, with effects appearing intensity-dependent and retreats yielding sustained advantages. Despite methodological limitations, Vipassana holds promise as an adjunct for stress-related disorders, warranting larger, well-controlled RCTs to substantiate its long-term efficacy.