Influenza vaccination has been reported to cause miller fisher syndrome. - GreenMedInfo Summary
Postvaccination miller fisher syndrome.
Arch Neurol. 2011 Oct ;68(10):1327-9. PMID: 21987549
Department of Medicine and Neurology, University of British Columbia, 1103-1068 W Broadway Ave, Vancouver, BC V6H 0A7, Canada. [email protected].
BACKGROUND: Although postvaccination Guillain-Barré syndrome is commonly reported, there have only been 2 previously reported cases of postvaccination Miller Fisher syndrome, and none in association with the novel influenza A(H1N1) vaccine.
OBJECTIVE: To describe a case of Miller Fisher syndrome following receipt of the seasonal influenza and novel influenza A(H1N1) vaccine.
DESIGN: Case report and literature review.
SETTING: Vancouver General Hospital. Patient A 77-year-old Chinese woman.
RESULTS: The patient presented with ophthalmoplegia, ataxia, areflexia, and a sensory neuropathy within 2 weeks of immunization. Findings of parainfectious evaluation were unremarkable. Treatment with 2 courses of intravenous immunoglobulin led to clinical improvement. Her presentation and natural history of disease were similar to the 2 previously published cases.
CONCLUSIONS: We present the third case of postvaccination Miller Fisher syndrome in the literature and the first associated with the novel influenza A(H1N1) vaccine.
