Abstract Title:

Inhibitory Potential of Red Cabbage against Digestive Enzymes Linked to Obesity and Type 2 Diabetes.

Abstract Source:

J Agric Food Chem. 2017 Aug 23 ;65(33):7192-7199. Epub 2017 Aug 9. PMID: 28753316

Abstract Author(s):

Anna Podsędek, Iwona Majewska, Alicja Z Kucharska

Article Affiliation:

Anna Podsędek


Assays of the inhibitory potential against enzymes involved in carbohydrate and lipid digestion (α-amylase, α-glucosidase, and lipase) as well as the total contents of phenolics and anthocyanins, anthocyanin profile, and antioxidant capacity revealed significant differences (p<0.05) between five varieties of red cabbage. Among the varieties, the highest inhibitory activity againstα-glucosidase (IC= 3.87± 0.12 mg dry weight (DW) of cabbage/mL) and lipase (IC= 1.57± 0.06 mg DW/mL) was exhibited by the Koda variety, which showed the highest antioxidant capacity in ABTS (Trolox equivalent antioxidant capacity (TEAC) = 141 ± 4.71 μmol/g DW) and ferric-reducing antioxidant power (TEAC = 125 ± 1.94 μmol/g DW) assays and had the highest total phenolics level (19.6 ± 0.48 mg/g DW). The highest total anthocyanin content (12.0 ± 0.16 mg/g DW) and inhibitory activity against α-amylase (IC= 69.0± 3.65 mg DW of cabbage/mL) was shown by the Kissendrup variety. The anthocyanin profiles of these two varieties were characterized by the highest percentages of diacylated cyanidin derivatives. There was no correlation between the contents of phenolic compounds and lipase inhibitory activity, butinhibition of α-amylase was correlated with concentrations of monoacylated and diacylated anthocyanins, while inhibition of α-glucosidase increased with total phenolics and diacylated anthocyanins levels.

Study Type : In Vitro Study

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