Article Publish Status: FREE
Abstract Title:

Insight into the pharmacological effects of andrographolide in musculoskeletal disorders.

Abstract Source:

Biomed Pharmacother. 2021 Dec 23 ;146:112583. Epub 2021 Dec 23. PMID: 34954644

Abstract Author(s):

Ming-Yang Liu, Hai-Jun Li, Chen Yang, Wei-Dong Zang, Zhen-Dong Liu, Liang Zhang, Pan-Hui Li, Yong-Jie Zhu, Yao-Ye Zhao, Run-Ze Liu, Yan-Zheng Gao

Article Affiliation:

Ming-Yang Liu


Andrographis paniculata (A. paniculata) is a traditional herbal medicine that has been widely used in Asian countries for hundreds of years. Andrographolide (AG) is a diterpene lactone extracted from A. paniculata. Owing to the in-depth study of pharmacological mechanisms, the therapeutic potential of AG, including its anti-inflammatory, anti-tumor, and immunoregulatory attributes, has attracted the attention of many researchers. Studies testing the therapeutic effects of AG have demonstrated desirable results in the treatment of a variety of clinical diseases. With high safety and various biological functions, AG might be a promising candidate for the treatment of musculoskeletal disorders. Here, we review all available literatures to summarize the pharmacological effects of AG and facilitate further researches on musculoskeletal diseases.

Study Type : Review

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Sayer Ji
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