Interactive effect of swimming training and fenugreek (L.) extract on glycemic indices and lipid profile in diabetic rats.
Arch Physiol Biochem. 2020 Oct 5:1-5. Epub 2020 Oct 5. PMID: 33017260
Seyed Ali Hosseini
Present study investigated the interactive effect of swimming training and fenugreek on glycemic index and lipid profile of diabetic rats. Forty-eight diabetic rats were randomly assigned to (1) control(C), (2) training(T), (3) fenugreek(F), and (4) training + fenugreek(T + F) groups and 12 healthy rats were placed in healthy control (HC) group. During 4 weeks, groups 2 and 4 performed swimming training for 5 sessions per week and groups 3 and 4 received 100 mg/kg fenugreek. training, fenugreek and training + fenugreek significantly decreased glucose, insulin, insulin resistance, LDL, VLDL, TG and TC as well as increased HDL ( ≤ .05) also training + fenugreek had more favourable effects on improving glycemic indices and lipid profile compared to training and fenugreek alone ( ≤ .05). It seems that training and fenugreek alone or synergistically improve the glycemic indices and lipid profile in diabetic rats, nevertheless the synergistic effects of training and fenugreek can be more desirable than the effect of each alone.