It is possible that lesions suggestive of Amyotrophic Lateral Sclerosis may be attributed to celiac disease. - GreenMedInfo Summary
White matter lesions suggestive of amyotrophic lateral sclerosis attributed to celiac disease.
BJU Int. 2007 Mar;99(3):619-22. Epub 2006 Nov 28. PMID: 19910450
SUMMARY: CD is an autoimmune-mediated disorder of the gastrointestinal tract. Initial symptom presentation is variable and can include neurologic manifestations that may comprise ataxia, neuropathy, dizziness, epilepsy, and cortical calcifications rather than gastrointestinal-hindering diagnosis and management. We present a case of a young man with progressive neurologic symptoms and brain MR imaging findings worrisome for ALS. During the diagnostic work-up, endomysium antibodies were discovered, and CD was confirmed by upper gastrointestinal endoscopy with duodenal biopsies. MR imaging findings suggestive of ALS improved after gluten-free diet institution.