Abstract Title:

[Multidisciplinary methodology and ketogenic diet in real clinical practice: efficacy and rapidity in weight loss. Survival Analysis PROMET Lipoinflammation study].

Abstract Source:

Nutr Hosp. 2020 May 7. Epub 2020 May 7. PMID: 32379476

Abstract Author(s):

Germán Guzmán, Ignacio Sajoux, Rocio Aller, Daniel de Luis

Article Affiliation:

Germán Guzmán


OBJECTIVE: the aim of the current work was to evaluate the response time to a method of weight loss that includes dietary guidelines, physical exercise and emotional support. The response was defined as a loss of 10% of the baseline weight.

METHODS: data was obtained from the patients' record recruited in Promet Lipoinflamación, an observational study of real world data in obese or overweight patients treated with a multidisciplinary method and based initially on a very-low-calorie ketogenic (VLCK) diet. Weight loss rate was evaluated through a survival analysis Kaplan-Meier and related factors through Cox regression).

RESULTS: 6,369 subjects were included and 74.4% managed to reach a weight loss of 10% in a mean time of 57.64 days (IC 95%: 56.95-58.33). The factors associated with a greater probability of reaching a loss of 10% or more were male gender (RR: 1.37, p<0.001), obesity types I, II and III vs. overweight (RR: 1.24, p<0.001, 1.26, p<0.001 and 1.22, p<0.001, respectively) and young age vs. more than 55 years old (RR: 2.17, p<0.001).

CONCLUSION: Results obtained through real clinical practice show that the method produces fast and intense weight loss. Three out of four patients lost at least 10% of body weight in an average of 58 days.

Study Type : Human Study

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Sayer Ji
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