Article Publish Status: FREE
Abstract Title:

Kombucha tea from seagrapes () potential as a functional anti-ageing food:andstudy.

Abstract Source:

Heliyon. 2021 Sep ;7(9):e07944. Epub 2021 Sep 8. PMID: 34541352

Abstract Author(s):

Happy Kurnia Permatasari, Fahrul Nurkolis, Piko Satria Augusta, Nelly Mayulu, Mury Kuswari, Nurpudji Astuti Taslim, Defny Silvia Wewengkang, Siti Chairiyah Batubara, William Ben Gunawan

Article Affiliation:

Happy Kurnia Permatasari


This study wants to investigate the effects of kombucha tea based on seagrapes on blood glucose levels, total cholesterol, and PGC-1α in Swiss albino mice that were given cholesterol- and fat-enriched diets (CFED). Anti-glycation, tyrosinase inhibitory, and α-glucosidase inhibitory activity were also determined. Forty male swiss webster albino mice weighing between 20 g-30 g were used for this study. Animals were distributed in random into 4 groups of 10 animals each; group A served as normal control (received standard dry pellet diet), group B were fed on CFED for 4 weeks, and groups C and D were fed on CFED and were administered 150 and 300 mg/kg of kombucha tea from seagrapes () (p.o.).study show that the activity of anti-glycation, L-Tyrosine, L-Dopa,α-glucosidase, and α-amylase inhibition were 62.79 ± 0.78, 9.05 ± 0.16, 27.14 ± 1.62, 90.42 ± 0.77, and 80.44 ± 1.00, respectively. Group C has a better activity in increasing PGC-1-alpha serum in mice than group D (p<0.05). There were no meaningful differences between group C and D in blood cholesterol and blood glucose reduction (p = 0.222), both groups have the same effect in lowering total cholesterol and blood glucose in mice. In conclusion, kombucha tea from seagrapes has potential as an anti-ageing functional food.

Study Type : Animal Study, In Vitro Study

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