L-cysteine attenuates the mutagenicity of the antiamebic drug diiodohydroxyquinoline in mice. - GreenMedInfo Summary
Abstract Title:
Bio-antimutagenic effect of L-cysteine on diiodohydroxyquinoline-induced micronuclei in Swiss mice.
Abstract Source:
Mutat Res. 1987 Apr;187(4):219-22. PMID: 3104778
Abstract:
The mutagenic potential of diiodohydroxyquinoline (DIHQ), a common anti-amebic drug, was tested using the in vivo micronucleus test in Swiss mice following oral administration. It was found to be mutagenic in a dose-dependent manner. Using the same model system, the bio-antimutagenic effect of the sulfhydryl compound L-cysteine against DIHQ was established.
Article Published Date : Apr 01, 1987
Study Type : Animal Study
Additional Links
Substances : Cysteine (see N-Acetylcysteine) : CK(111) : AC(33), NAC (N-acetyl-L-cysteine) : CK(1429) : AC(366)
Diseases : Amebiasis : CK(26) : AC(6)
Additional Keywords : Drug-Plant-Vitamin Synergies : CK(965) : AC(266)
