Abstract Title:

The effect of L-tryptophan on seasonal affective disorder.

Abstract Source:

Water Res. 2002 Sep;36(15):3821-33. PMID: 2182615

Abstract Author(s):

R E McGrath, B Buckwald, E V Resnick


Serotonin has been implicated in the etiology of seasonal affective disorder (SAD). The authors compared the effect of the serotonergic precursor L-tryptophan, placebo, and artificial evening light on 13 SAD sufferers. L-Tryptophan and light were associated with greater improvement than was placebo, but the antidepressant effects of L-tryptophan and light were not significantly different.


Study Type : Human Study

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