Abstract Title:

B-Group vitamin production by lactic acid bacteria - current knowledge and potential applications.

Abstract Source:

J Appl Microbiol. 2011 Sep 20. Epub 2011 Sep 20. PMID: 21933312

Abstract Author(s):

J G Leblanc, J E Laiño, M Juarez Del Valle, V Vannini, D van Sinderen, M P Taranto, G Font de Valdez, G Savoy de Giori, F Sesma

Article Affiliation:

 Centro de Referencia para Lactobacilos (CERELA-CONICET) Chacabuco 145, Tucumán, Argentina  Department of Microbiology and Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland  Cátedra de Microbiología Superior, Universidad Nacional de Tucumán (UNT), Tucumán, Argentina.


Although most vitamins are present in a variety of foods, human vitamin deficiencies still occur in many countries, mainly because of malnutrition not only as a result of insufficient food intake but also because of unbalanced diets. Even though most lactic acid bacteria (LAB) are auxotrophic for several vitamins, it is now known that certain strains have the capability to synthesize water-soluble vitamins such as those included in the B-group (folates, riboflavin and vitamin B(12) amongst others). This review article will show the current knowledge of vitamin biosynthesis by LAB and show how the proper selection of starter cultures and probiotic strains could be useful in preventing clinical and subclinical vitamin deficiencies. Here, several examples will be presented where vitamin-producing LAB led to the elaboration of novel fermented foods with increased and bioavailable vitamins. In addition, the use of genetic engineering strategies to increase vitamin production or to create novel vitamin-producing strains will also be discussed. This review will show that the use of vitamin-producing LAB could be a cost-effective alternative to current vitamin fortification programmes and be useful in the elaboration of novel vitamin-enriched products.

Study Type : Review

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