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Article Publish Status: FREE
Abstract Title:

Evaluation of antioxidative effects ofwith fuzzy synthetic models.

Abstract Source:

J Microbiol Biotechnol. 2018 May 8. Epub 2018 May 8. PMID: 29913548

Abstract Author(s):

Jichun Zhao, Fengwei Tian, Shuang Yan, Qixiao Zhai, Hao Zhang, Wei Chen

Article Affiliation:

Jichun Zhao

Abstract:

Numerous studies suggest that the effects of lactic acid bacteria (LAB) on oxidative stressare correlated with their antioxidative activities, however the relationship is still unclear and contradictory. The antioxidative activities of 27strains isolated from fermented foods were determined with 2, 2-diphenyl-1-picrylhydrazyl, hydroxyl radicals and superoxide radical scavenging ability, reducing activity, resistance to hydrogen peroxide and ferrous chelating ability. Two fuzzy synthetic evaluation models, one with an analytic hierarchy process and one using entropy weight, were then used to evaluate the overall antioxidative abilities of thesestrains. Although there was some difference between the two models, the highest scoring strain (CCFM10), the middle scoring strain (CCFM242) and the lowest scoring strain (RS15-3) were obtained with both models. The examination of the antioxidative abilities of three strains in D-galactose-induced oxidative stress mice demonstrated that their overall antioxidative abilitiescould reveal the abilities to alleviate oxidative stress. The current study suggests that assessment of overall antioxidative abilities with fuzzy synthetic models can guide evaluation of probiotic antioxidants. It might be a more quick and effective method to evaluate the overall antioxidative abilities of LAB.

Study Type : In Vitro Study

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