Abstract Title:

Quantitative Analysis of Phenolic Acids and Antiplatelet Activity of Melissa officinalis Leaf Extracts.

Abstract Source:

Nat Prod Commun. 2017 Jan ;12(1):93-94. PMID: 30549835

Abstract Author(s):

Željan Maleš, Andrea Antolić, Ivana Babić, Sandra Jurić, Mirza Bojić

Article Affiliation:

Željan Maleš


The contents of total phenolic acids and rosmarinic acid were determined and the antiplatelet potential assessed of extracts of lemon balm (Melissa officinalis L., Lamiaceae) leaf samples collected during 2014 and 2015. The quantity of total phenolic acids ranged from 4.8 to 8.5%, while the rosmarinic acid content ranged from 1.78 to 4.35%. Results of statistical analysis showed that the undiluted extracts have antiplatelet activity in the ADP test (final concentration 31.25 mg/L). While there are reports on antiplatelet activity of lemon balm essential oil, to the best of our knowledge, this is the first report on antiplatelet activity of lemon balm leaf extracts.

Study Type : In Vitro Study

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