Abstract Title:

Lignans and Terpenoids from the Leaves of Schisandra chinensis.

Abstract Source:

Chem Biodivers. 2020 Mar 5. Epub 2020 Mar 5. PMID: 32141193

Abstract Author(s):

Bing-You Yang, Guo-Zhen Liu, Yan Liu, Yan-Ping Sun, Xiao-Mao Li, Zhen-Peng Xu, Peng Jiang, Xiao-Hui Rong, Hai-Xue Kuang

Article Affiliation:

Bing-You Yang


Fifteen constituents, include one new lignan (schisandroside E, 1) and one new terpenoid (schisandenoid A, 2) as well as nine known lignans and four known terpenoids, were isolated from Schisandra chinensis leaves. The structures of compounds 1-2 were established by entirely meticulous spectroscopic analysis (NMR, MS, CD, IR and UV). All compounds were tested for cytotoxicity against MGC-803, Caco-2 and Ishikawa cell lines. Some compounds showed strong cytotoxicity against these three cancer cell lines with IC50﹤1 μM.

Study Type : In Vitro Study

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Sayer Ji
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