Abstract Title:

Liver fibrosis attributed to lipid lowering medications: two cases.

Abstract Source:

J Intern Med. 2001 Sep ;250(3):249-54. PMID: 11555130

Abstract Author(s):

Z Punthakee, L J Scully, M M Guindi, T C Ooi

Article Affiliation:

Department of Medicine, The Ottawa Hospital - Civic Campus, University of Ottawa, Ottawa, Ontario, Canada.


We identified two cases of chronic active hepatitis with liver fibrosis induced by lipid lowering drugs of the statin and fibrate classes despite regular monitoring of transaminases. There are few reports of clinically significant hepatitis induced by these drugs and even fewer cases of fibrosis. Given the growing use of these drugs, there are implications for monitoring patients on long-term therapy for liver damage.

Study Type : Human: Case Report

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