Abstract Title:

The Effectiveness of Lactobacillus Beverages in Controlling Infections among the Residents of an Aged Care Facility: A Randomized Placebo-Controlled Double-Blind Trial.

Abstract Source:

Ann Nutr Metab. 2016 ;68(1):51-9. Epub 2015 Nov 25. PMID: 26599038

Abstract Author(s):

Satoru Nagata, Takashi Asahara, Chongxin Wang, Yumi Suyama, Osamu Chonan, Kikuo Takano, Masashi Daibou, Takuya Takahashi, Koji Nomoto, Yuichiro Yamashiro

Article Affiliation:

Satoru Nagata


BACKGROUNDS/AIMS: To clarify the usefulness of Lactobacillus casei strain Shirota (LcS)-fermented milk in the normalization of bowel movements and improvement of infection control for the elderly residents and staff of facilities for the elderly.

METHODS: A randomized placebo-controlled double-blind test was performed among the elderly residents (average age, 85) and staff members (average age, 37) of facilities for the elderly. The participants randomly received either LcS-fermented milk or a placebo beverage once daily for 6 months. Clinical data and enteric conditions were compared between the 2 groups.

RESULTS: A significantly lower incidence of fever and improved bowel movements were seen in the LcS-fermented milk group (n = 36) in comparison to the placebo group (n = 36). The numbers of Bifidobacterium and Lactobacillus were significantly higher (p<0.01), the numbers of destructive bacteria such as Clostridium difficile were significantly lower (p<0.05), and the fecal acetic acid concentration and total acidity were significantly higher in the LcS group. A significant difference in the intestinal microbiota, fecal acetic acid, and pH was also observed between the LcS and placebo groups among the facility's staff members.

CONCLUSIONS: The long-term consumption of LcS-fermented milk may be useful for decreasing the daily risk of infection and improving the quality of life among the residents and staff of facilities for the elderly.

Study Type : Human Study

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