n/a
Abstract Title:

Long-term exposure to PMand stroke: A systematic review and meta-analysis of cohort studies.

Abstract Source:

Environ Res. 2019 Oct ;177:108587. Epub 2019 Jul 15. PMID: 31326714

Abstract Author(s):

Sheng Yuan, Jiaxin Wang, Qingqing Jiang, Ziyu He, Yuchai Huang, Zhengyang Li, Luyao Cai, Shiyi Cao

Article Affiliation:

Sheng Yuan

Abstract:

BACKGROUND: Stroke is one of the world's leading causes of death. Many studies have checked the relationship between short-term exposure to particulate matter (PM) and stroke, but few have focused on the effect of long-term exposure to PM(particulate matters with an aerodynamic diameter of≤2.5 μm). This study aimed to quantitatively examine the relationship of long-term exposure to PMwith stroke incidence and mortality.

METHODS: We identified relevant studies by searching the PubMed, EMBASE and MEDLINE. After the systematical review of pertinent studies, random-effect meta-analysis was conducted to investigate the association between long-term exposure to PMand stroke.

RESULTS: Our meta-analysis included 16 cohort studies with more than 2.2 million people and above 49 149 endpoint events (incident stroke and death from stroke). The pooled hazard ratio (HR) for each 5 μg/mincrement in PMwas 1.11 (95% CI: 1.05, 1.17) (CI for confidence interval) for incidence of stroke and 1.11 (95% CI:1.05, 1.17) for mortality of stroke. In the region-specific analysis, significant association between PMand incidence of stroke was found in North America (HR=1.09, 95% CI:1.05, 1.14) and Europe (HR=1.07, 95% CI:1.05, 1.10), while the pooled result of Asia showed no significance (HR=2.31, 95% CI:0.49, 10.95).

CONCLUSIONS: Long-term exposure to PMis an important risk factor for stroke. Since air quality is intimately related to everyone, policies aimed at reducing particulate matters will benefit public health a lot.

Study Type : Meta Analysis, Review

Print Options


Key Research Topics

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2024 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.