Abstract Title:

A mango (Mangifera indica L.) juice by-product reduces gastrointestinal and upper respiratory tract infection symptoms in children.

Abstract Source:

Food Res Int. 2020 Oct ;136:109492. Epub 2020 Jun 26. PMID: 32846573

Abstract Author(s):

Miriam A Anaya-Loyola, Gabriela García-Marín, David G García-Gutiérrez, Eduardo Castaño-Tostado, Rosalía Reynoso-Camacho, Juan E López-Ramos, José A Enciso-Moreno, Iza F Pérez-Ramírez

Article Affiliation:

Miriam A Anaya-Loyola


The study aimed to evaluate the effect of a mango juice by-product (JBP) on upper-respiratory and gastrointestinal tract infection symptoms in children (6-8 y) in a randomized, double-blind, parallel, case-control study. For two months, children drank either flavored water (control group) or a mango JBP-based beverage (0.04 g·ml; treatment group); such beverage provided 1.1 g, 278.6 mg and 7.8 mg of dietary fiber, extractable polyphenols (mono-to-hepta galloyl hexosides, mangiferin), and hydrolysable polyphenols (ellagic/gallic acid) per portion, respectively. Mango JBP reduced the incidence of gastrointestinal (flatulencies and abdominal inflammation; p ≤ 0.007) and upper-tract respiratory (crystalline mucus, itchy throat, runny nose, itchy nose, and sneezing; p ≤ 0.038) and such benefits were associated to increased serum levels of PAI-I, MIP-1a, and MIP-1b (p ≤ 0.04) and decreased levels of IgG, MIF, and osteopontin (p ≤ 0.01). We concludedthat JBP-based beverage has immunomodulatory properties, useful to prevent or even treat common infectious diseases in school-age children.

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