Mastic gum inhibits Helicobacter pylori. - GreenMedInfo Summary
Bactericidal activity of Pistacia lentiscus mastic gum against Helicobacter pylori.
Fertil Steril. 2009 Feb;91(2):597-601. Epub 2008 Feb 21. PMID: 11806621
In this study we evaluated the antibacterial activity of mastic gum, a resin obtained from the Pistacia lentiscus tree, against clinical isolates of Helicobacter pylori. The minimal bactericidal concentrations (MBCs) were obtained by a microdilution assay. Mastic gum killed 50% of the strains tested at a concentration of 125 microg/ml and 90% at a concentration of 500 microg/ml. The influence of sub-MBCs of mastic gum on the morphologies of H. pylori was evaluated by transmission electron microscopy. The lentiscus resin induced blebbing, morphological abnormalities and cellular fragmentation in H. pylori cells.