Abstract Title:

Maternal anaphylaxis and fetal brain damage after intrapartum chemoprophylaxis.

Abstract Source:

J Perinat Med. 2004;32(4):375-7. PMID: 15346827

Abstract Author(s):

Alberto Berardi, Katia Rossi, Francesca Cavalleri, Angela Simoni, Lorenzo Aguzzoli, Giuseppe Masellis, Fabrizio Ferrari

Article Affiliation:

Neonatal Intensive Care Unit, Azienda Policlinico, Modena, Italy. [email protected]


We report a case of maternal anaphylaxis following intrapartum chemoprophylaxis. The term fetus developed severe brain damage as a consequence of intrapartum asphyxia. The lesions resulted from maternal hypotension following anaphylaxis. We discuss the feto-maternal risks and the controversial treatment of such a condition. The increasing number of penicillin-treated parturients will result in further cases of maternal anaphylaxis than previously found.

Study Type : Human: Case Report

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