Abstract Title:

Effect of combined maternal and infant vitamin D supplementation on vitamin D status of exclusively breastfed infants.

Abstract Source:

Matern Child Nutr. 2009 Jan;5(1):25-32. PMID: 19161542

Abstract Author(s):

Hussein F Saadi, Adekunle Dawodu, Bachar Afandi, Reem Zayed, Sheela Benedict, Nicolaas Nagelkerke, Bruce W Hollis


Severe vitamin D deficiency in mothers and their breastfed infants is a significant health problem in the Middle East. Supplementation of the breastfed infant alone with the recommended dose of vitamin D may be insufficient in high-risk population. We investigated the effect of combined maternal and infant vitamin D supplementation on vitamin D status of the breastfed infant. We examined also the effect of supplementation on vitamin D antirachitic activity of breast milk in a subset of mothers. Healthy breastfeeding mothers (n = 90) were randomly assigned to 2000 IU daily (group 1) or 60,000 IU monthly (group 2) of vitamin D(2), and all their infants (n = 92) received 400 IU daily of vitamin D(2) for 3 months. Most infants had vitamin D deficiency - 25-hydroxyvitamin D [25(OH)D]

Study Type : Human Study

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