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Article Publish Status: FREE
Abstract Title:

Medicinal potential ofand its ginsenosides in atopic dermatitis treatment.

Abstract Source:

J Ginseng Res. 2020 Jan ;44(1):8-13. Epub 2019 Jan 7. PMID: 32095092

Abstract Author(s):

Laura Rojas Lorz, Mi-Yeon Kim, Jae Youl Cho

Article Affiliation:

Laura Rojas Lorz

Abstract:

Atopic dermatitis (AD) is a chronic and relapsing inflammatory disease that affects 1%-20% of people worldwide. Despite affecting many people, AD current treatments, such as corticosteroids and calcineurin inhibitors, have not only harmful secondary effects but are also often ineffective. Therefore, natural nontoxic compounds are on high demand for developing new effective AD treatments.Meyer has been used traditionally for its promising healing and restorative properties to treat many diseases including skin disorders, reason why in this review we want to explore the research performed with AD andas well as determining its potential for new drug development. Previous researches have shown thathas positive effects in AD patients such as lower eczema area and severity index, transepidermal water loss, and immunoglobulin E levels and better quality of sleep.animal models, as well, have shown positive results toand derived ginsenosides, such as the decrease of transepidermal water loss, immunoglobulin E levels in serum, allergy-related cytokines, and downregulation of NF-κB, MAPK, and Ikaros pathways. All of these previous data suggest thatand its derived ginsenosides are undoubtedly a nontoxic effective option to treat AD.

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