Abstract Title:

Metastatic melanoma with spontaneous regression, psoriasis and HLA-Cw6: case report and a hypothesis to explore.

Abstract Source:

Tumori. 2014 Jul-Aug;100(4):144e-7e. PMID: 25296606

Abstract Author(s):

Sara Pérez Ramírez, Verónica Parra, José Antonio Avilés Izquierdo, José Luis Vicario, Miguel Martín, Iván Márquez-Rodas

Article Affiliation:

Sara Pérez Ramírez


Spontaneous regressions of metastatic melanoma are rare, but several cases have been described in the literature. Although the mechanism of the phenomenon is not well understood, it is postulated that an activation of the immune system is behind it. Here we report the case of a patient with metastatic melanoma that, without any treatment, regressed spontaneously. The patient presented psoriasis (a disease of the skin related with autoimmunity) linked with HLA-Cw6. We review the literature and hypothesize with the possible relationship between psoriasis, HLA-Cw6 and the spontaneous regression.

Study Type : Human: Case Report

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