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Article Publish Status: FREE
Abstract Title:

Microbiota diversity and bacterial load after successful treatment ofinfection with honey lavage in 4 patients.

Abstract Source:

Biosci Microbiota Food Health. 2022 ;41(1):1-3. Epub 2021 Sep 30. PMID: 35036247

Abstract Author(s):

Yara M W VAN Knippenberg, Robert J F Laheij

Article Affiliation:

Yara M W VAN Knippenberg

Abstract:

In this letter, an experimental therapy in four patients with therapy-resistantinfection is described. These four patients were treated with Manuka honey via colon lavage. First, the patients received a three-day fidaxomicin treatment. The colon lavage was performed on the third day. During a subsequent ileocolonoscopy, 300 mL 15% Manuka honey was applied via a spray catheter. Patients remained in bed for two hours after the procedure and did not defecate. The patient's microbiomes were tested before treatment, after the fidaxomicin treatment, and after honey lavage. A decrease inload was found in their microbiomes. Additionally, restoration of microbiota diversity after the honey lavage was also noted. The four patients experienced complete cessation of watery stools and remain symptom free. These results indicate the need for more clinical research into this matter.

Study Type : Human Study

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