Article Publish Status: FREE
Abstract Title:

Mindfulness effects on lifestyle behavior and blood pressure: A randomized controlled trial.

Abstract Source:

Health Sci Rep. 2021 Jun ;4(2):e296. Epub 2021 Jun 5. PMID: 34136657

Abstract Author(s):

Eunjoo An, Michael R Irwin, Lynn V Doering, Mary-Lynn Brecht, Karol E Watson, Elizabeth Corwin, Paul M Macey

Article Affiliation:

Eunjoo An


Background and aims: HTN affects nearly 50% of U.S. adults and is the leading modifiable cardiovascular risk factor. A healthy diet and exercise can improve BP control, but adherence to these interventions is low. We tested whether a multimodal mind-body program, Mindful Awareness Practices (MAP) could improve BP and lifestyle behaviors associated with HTN when compared to a Health Promotion Program (HPP).

Methods: Adults with BP>120/80 were randomized to MAP or HPP. Outcome measurements of BP, self-reported diet, and exercise were analyzed with intent-to-treat group comparisons using repeated measures linear mixed models.

Results: There was an MAP-HPP between-group difference in interactions of time-by-systolic BP ( = 0.005) and time-by-diastolic BP ( = .003). The mean drops in SBP from baseline to week 13 for the MAP group was 19 mm Hg (138 ± 15 mm Hg-119 ± 6 mm Hg) compared to 7 mm Hg (134 ± 18 mm Hg-127 ± 22 mm Hg) in the HPP group. Similarly, a greater reduction in DBP was observed in the MAP group comparedto the HPP group, 12 mm Hg (89 mm Hg ± 11-77 ± 7 mm Hg) and 1 mm Hg (81 ± 16 mm Hg-80 ± 18 mm Hg), respectively. Mediational analysis of the MAP group showed the total effect of mindfulness practice minutes on SBP with indirect effect (ab) of -.057 was significant, resulting in a 40% lower SBP for total effect (c) compared to direct (c') effect alone. The mediational model suggests MAP has a modest positive influence on participants initiating lifestyle behavior change, which partially explains the greater reduction in BP by the MAP group.

Conclusion: Our findings suggest a multimodal mind-body program involving mindfulness practice may improve BP control in adults with HTN.

Study Type : Human Study

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