Abstract Title:

Mushroom extracts and compounds with suppressive action on breast cancer: evidence from studies using cultured cancer cells, tumor-bearing animals, and clinical trials.

Abstract Source:

Appl Microbiol Biotechnol. 2020 Jun ;104(11):4675-4703. Epub 2020 Apr 9. PMID: 32274562

Abstract Author(s):

Jack Ho Wong, Tzi Bun Ng, Helen Hei Ling Chan, Qin Liu, Gene Chi Wai Man, Chris Zhiyi Zhang, Suzhen Guan, Charlene Cheuk Wing Ng, Evandro Fei Fang, Hexiang Wang, Fang Liu, Xiuyun Ye, Krzysztof Rolka, Ryno Naude, Shuang Zhao, Ou Sha, Chunman Li, Lixin Xia

Article Affiliation:

Jack Ho Wong


This article reviews mushrooms with anti-breast cancer activity. The mushrooms covered which are better known include the following: button mushroom Agaricus bisporus, Brazilian mushroom Agaricus blazei, Amauroderma rugosum, stout camphor fungus Antrodia camphorata, Jew's ear (black) fungus or black wood ear fungus Auricularia auricula-judae, reishi mushroom or Lingzhi Ganoderma lucidum, Ganoderma sinense, maitake mushroom or sheep's head mushroom Grifola frondosa, lion's mane mushroom or monkey head mushroom Hericium erinaceum, brown beech mushroom Hypsizigus marmoreus, sulfur polypore mushroom Laetiporus sulphureus, Lentinula edodes (shiitake mushroom), Phellinus linteus (Japanese"meshimakobu,"Chinese"song gen,"Korean"sanghwang,"American"black hoof mushroom"), abalone mushroom Pleurotus abalonus, king oyster mushroom Pleurotus eryngii, oyster mushroom Pleurotus ostreatus, tuckahoe or Fu Ling Poria cocos, and split gill mushroom Schizophyllum commune. Antineoplastic effectiveness in human clinical trials and mechanism of anticancer action have been reported for Antrodia camphorata, Cordyceps sinensis, Coriolus versicolor, Ganoderma lucidum, Grifola frondosa, and Lentinula edodes.

Study Type : Animal Study, In Vitro Study

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