Myrrh contains sesquiterpenes with anaesthetic, antibacterial and antifungal properties. - GreenMedInfo Summary

Abstract Title:

Local anaesthetic, antibacterial and antifungal properties of sesquiterpenes from myrrh.

Abstract Source:

Planta Med. 2000 May;66(4):356-8. PMID: 10865454

Abstract Author(s):

P Dolara, B Corte, C Ghelardini, A M Pugliese, E Cerbai, S Menichetti, A Lo Nostro

Abstract:

We extracted, purified and characterized 8 sesquiterpene fractions from Commyphora molmol. In particular, we focused our attention on a mixture of furanodiene-6-one and methoxyfuranoguaia-9-ene-8-one, which showed antibacterial and antifungal activity against standard pathogenic strains of Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and Candida albicans, with minimum inhibitory concentrations ranging from 0.18 to 2.8 micrograms/ml. These compounds also had local anaesthetic activity, blocking the inward sodium current of excitable mammalian membranes.

Article Published Date : May 01, 2000
Study Type : In Vitro Study
Additional Links
Substances : Myrrh : CK(133) : AC(61)
Diseases : Bacterial Infections and Mycoses : CK(129) : AC(55), Pain : CK(1440) : AC(233)
Pharmacological Actions : Anti-Bacterial Agents : CK(4228) : AC(1989), Antifungal Agents : CK(730) : AC(422)

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Key Research Topics

Substance

Myrrh

Disease

Bacterial Infections and Mycoses
Pain

Pharmacological Actions

Anti-Bacterial Agents
Antifungal Agents

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