A natural flavonoid present in unripe plantain banana pulp (Musa sapientum L. var. paradisiaca) protects the gastric mucosa from aspirin-induced erosions. - GreenMedInfo Summary

Abstract Title:

A natural flavonoid present in unripe plantain banana pulp (Musa sapientum L. var. paradisiaca) protects the gastric mucosa from aspirin-induced erosions.

Abstract Source:

J Ethnopharmacol. 1999 Jun;65(3):283-8. PMID: 10404428

Abstract Author(s):

D A Lewis, W N Fields, G P Shaw

Article Affiliation:

Department of Pharmacy, Aston University, Gosta Green, Birmingham, UK.

Abstract:

The active anti-ulcerogenic ingredient was extracted from unripe plantain banana by solvent fractionation and identified by chromatography, spectroscopy and high performance liquid chromatography as the flavonoid leucocyanidin. Dried unripe plantain banana powder, the extracted leucocyanidin and a purified synthetic leucocyanidin demonstrated a significant (P<0.05) protective effect against aspirin-induced erosions.

Article Published Date : Jun 01, 1999
Study Type : Animal Study
Additional Links
Substances : Banana : CK(375) : AC(130), Flavonoids : CK(4692) : AC(2171)
Diseases : Aspirin-Induced Toxicity : CK(186) : AC(58), NSAID-induced toxicity : CK(1142) : AC(418)
Pharmacological Actions : Anti-Ulcer Agents : CK(842) : AC(282)

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Key Research Topics

Pharmacological Actions

Anti-Ulcer Agents

Substance

Flavonoids
Banana

Disease

NSAID-induced toxicity
Aspirin-Induced Toxicity

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