Article Publish Status: FREE
Abstract Title:

Neuroprotective effects ofand its constituent, linalool: A review.

Abstract Source:

Avicenna J Phytomed. 2021 Sep-Oct;11(5):436-450. PMID: 34745916

Abstract Author(s):

Mahmoud Hosseini, Mohammad Hossein Boskabady, Mohammad Reza Khazdair

Article Affiliation:

Mahmoud Hosseini


Objective: Coriander (L.) is an annual herb belonging to the Apiaceae (Umbellifera) family that is used as food additives traditionally. This plant is called "" in Persian and is native to Mediterranean regions but it is currently cultivated in several countries. All parts of coriander are edible and have been traditionally used to treat different disorders, including digestive problems, flatulence, diarrhea, colic and other gastrointestinal diseases.

Materials and Methods: The databases PubMed, Web of Science, Google Scholar and Scopus were considered. The search terms were "" or "linalool" and "anti-anxiety", "sedative", "antioxidant effect", "anticonvulsant" and "neuroprotective effect".

Results: Antioxidant, diuretic, cholesterol lowering, anxiolytic, sedative-hypnotic and anticonvulsant activities were reported for the seeds and leaves of the plant. Furthermore, linalool as the main component of coriander has different neuropharmacological effects, including anti-anxiety, sedative, anticonvulsant and anti-Alzheimer's disease activities.

Conclusion: Various neuropharmacological effects ofand its component which have antioxidant and anti-inflammatory effects, have been summarized in the current review article.

Study Type : Review

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