Abstract Title:

Neuroprotective Potency of Safranal Against Neurological Disorders.

Abstract Source:

Curr Mol Med. 2022 Nov 17. Epub 2022 Nov 17. PMID: 36397621

Abstract Author(s):

Elham Fazeli, Mohammad Hossein Eshaghi Ghalibaf, Fatemeh Forouzanfar

Article Affiliation:

Elham Fazeli


A great number of research has been focused on plants as a source of medicine against many diseases to overcome the many side effects of chemical drugs. Safranal, one of the main constituents of saffron [Crocus sativus], has a broad spectrum of pharmacological effects, including anti-inflammatory, antioxidant, and antiapoptotic effects. The present review elaborates on the current understanding of the neuroprotective effects of safranal. According to data published so far, safranal has the potential to exert neuroprotective effects in neurological disorders such as epilepsy, stroke, multiple sclerosis, Parkinson, and Alzheimer's disease. Safranal could be considered a promising therapeutic agent in the future, although there is a great need for clinical trial studies.

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