Abstract Title:

[Adverse effects of the human papillomavirus vaccine].

Abstract Source:

Aten Primaria. 2010 Dec 14. Epub 2010 Dec 14. PMID: 21163554

Abstract Author(s):

M Amparo Torrecilla Rojas, Miguel Pedregal González, Fermín García Rodríguez, Josefa Ruiz Fernández

Article Affiliation:

Distrito Condado-Campiña, Huelva, España.


OBJECTIVE: To describe the most frequent adverse reactions produced by the human papillomavirus (HPV) vaccine. DESIGN: Cross-sectional descriptive study using a telephone survey. SETTING: A province in the Andalusian Public Health System. PARTICIPANTS: Females vaccinated against HPV in Andalusia, selected by simple random sampling representative of the province. MAIN MEASUREMENTS: A total of 3,135 telephone calls were made by the public service "Health Answers" using telephone operators supervised by health personnel. RESULTS: Of the 2,880 calls that fulfilled the inclusion criteria, 1,207 people (41.9% response) took part in the survey. Of the 2,124 surveys made there was some type of adverse reaction (fever, inflammation, pain or rash) in 467 doses (22%): 6.6% was fever, 49.5% inflammation, 72.4% pain, and 6% a rash. CONCLUSIONS: It can be said that HPV vaccine is safe, which is in agreement with that published in the summary of the product characteristics and in the literature.

Study Type : Human Study

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Sayer Ji
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