Onion and garlic both have anfungal activity against 18 strains of yeasts and dermatophytes. - GreenMedInfo Summary

Abstract Title:

In vitro antifungal activities of Allium cepa, Allium sativum and ketoconazole against some pathogenic yeasts and dermatophytes.

Abstract Source:

Pharmacol Res. 2010 Feb;61(2):142-8. Epub 2009 Sep 9. PMID: 16690223

Abstract Author(s):

Masoomeh Shams-Ghahfarokhi, Mohammad-Reza Shokoohamiri, Nasrin Amirrajab, Behnaz Moghadasi, Ali Ghajari, Farideh Zeini, Golnar Sadeghi, Mehdi Razzaghi-Abyaneh

Abstract:

By using an agar dilution assay, the antifungal activity of aqueous extracts prepared from Allium cepa (onion; AOE) and Allium sativum (garlic; AGE) were evaluated against Malassezia furfur (25 strains), Candida albicans (18 strains), other Candida sp. (12 strains) as well as 35 strains of various dermatophyte species and compared with the activity of a known antifungal drug, ketoconazole (KTZ). All the AOE, AGE and KTZ were found to be able to inhibit growth of all fungi tested in a dose-dependent manner with maximum of 100% at defined concentrations. The results indicate that onion and garlic might be promising in treatment of fungal-associated diseases from important pathogenic genera Candida, Malassezia and the dermatophytes.

Article Published Date : Feb 01, 2010
Study Type : In Vitro Study
Additional Links
Substances : Garlic : CK(2192) : AC(726), Onion : CK(510) : AC(150)
Diseases : Candidiasis : CK(486) : AC(227), Dermatophytoses : CK(3) : AC(4)
Pharmacological Actions : Antifungal Agents : CK(718) : AC(414)

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Key Research Topics

Substance

Garlic
Onion

Disease

Candidiasis
Dermatophytoses

Pharmacological Actions

Antifungal Agents

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