Oral intake of Pycnogenol might have the potential to reduce hair loss in postmenopausal women. - GreenMedInfo Summary
An oral French maritime pine bark extract improves hair density in menopausal women: A randomized, placebo-controlled, double blind intervention study.
Health Sci Rep. 2023 Jan ;6(1):e1045. Epub 2023 Jan 6. PMID: 36620515
Carr Cai
BACKGROUND AND AIMS: Female pattern hair loss affects females of all ages with a trend to increase after menopause. This disorder may have significant psychological impact and lead to anxiety and depression.
OBJECTIVE: In a single center, double blind, randomized, placebo-controlled study, the effects of oral Pycnogenol®intake (3 × 50 mg/day for a total of 6 months) on hair density, scalp microcirculation, and a variety of skin physiological parameters was studied in Han Chinese menopausal women ( = 76) in Shanghai, China.
METHODS: Measurements were taken at the beginning and after 2 and 6 months, respectively. Hair density was determined by digital photographs and further evaluated by Trichoscan software. Transepidermal water loss was measured by a humidity sensor in a closed chamber on the skin surface. Changes in microcirculation were detected as resting flux on the scalp by reflection photoplethysmography.
RESULTS: Pycnogenol®intake significantly increased hair density by 30% and 23% after 2 and 6 months of treatment, respectively, as detected by Trichoscan®evaluation of digital photographs. Interestingly, photoplethysmography revealed that this beneficial effect was associated with a decrease in resting flux of the scalp skin, which might indicate an improvement of microcirculation. None of these effects were observed in the placebo taking group. In addition, a significant transient decrease of transepidermal water loss was observed in scalp skin under Pycnogenol,® but not placebo treatment.
CONCLUSION: Oral intake of Pycnogenol®might have the potential to reduce hair loss in postmenopausal women.