Osteoporosis rates are higher in adult patients with celiac disease. - GreenMedInfo Summary
Osteoporosis in adult patients with celiac disease.
Bone. 1999 Mar;24(3):249-55. PMID: 10071918
Department of Clinical Nutrition, Kuopio University Hospital and University of Kuopio, Finland. [email protected]
We investigated the bone mineral density (BMD) and prevalence of osteopenia and osteoporosis in adult celiac patients with varying disease states. In this cross-sectional study the data on the severity of celiac disease and BMD were collected from 77 celiac patients (28 newly diagnosed and 49 previously diagnosed celiac patients), and BMD results were compared with those of 157 control subjects matched for age, gender, and menopausal status. The celiac patients had significantly lower BMD than the control subjects at the lumbar spine (-6%) and femoral neck (-5%). The mean BMD did not differ significantly among celiac patients classified by severity of disease. Based on Z scores, 35% of the celiac patients and 17% of the control subjects had low BMDs for age at the lumbar spine (p = 0.005), whereas 31% of celiac patients and 16% of control subjects had Z scores of