Abstract Title:

Effect of dried fruits of Carica papaya Linn on hepatotoxicity.

Abstract Source:

Biol Pharm Bull. 2002 Dec;25(12):1645-6. PMID: 12499657

Abstract Author(s):

Balasubramanian Rajkapoor, Balasundaram Jayakar, Subramanian Kavimani, Narayanan Murugesh

Article Affiliation:

Department of Pharmacology, Vinayaka Mission's College of Pharmacy, Salem, Tamil Nadu, India. [email protected]

Abstract:

Ethanol and aqueous extracts of Carica papaya has been evaluated for its anti hepatotoxic activity. The ethanol and aqueous extracts of Carica papaya showed remarkable hepatoprotective activity against CCl(4) induced hepatotoxicity. The activity was evaluated by using biochemical parameters such as serum aspartate amino transferase (AST), alanine amino transferase (ALT), alkaline phosphatase, total bilirubin and gamma glutamate transpeptidase (GGTP). The histopathological changes of liver sample was compared with respect to control.

Study Type : Animal Study

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