Abstract Title:

Passive immunity against measles during the first 8 months of life of infants born to vaccinated mothers or to mothers who sustained measles.

Abstract Source:

Vaccine. 1997 Apr-May;15(6-7):620-3. PMID: 9178461

Abstract Author(s):

G De Serres, J R Joly, M Fauvel, F Meyer, B Mâsse, N Boulianne

Article Affiliation:

G De Serres


Neutralizing antibody titers of 47 infants whose mothers sustained measles (measles group) and 70 whose mothers were vaccinated (vaccine group) were compared at birth, 4 and 8 months of age. All children had antibodies at birth and 88% at 4 months. At 8 months, 49% had antibodies in the measles group and 15% in the vaccine group (P<0.001). The geometric mean titers were significantly lower in the vaccine group than in the measles group and the difference corresponded to the antibody loss occurring in only 1.5 months of life. This small difference may reflect past exposure to wild virus of many vaccinated mothers.

Study Type : Human Study

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Sayer Ji
Founder of GreenMedInfo.com

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