Abstract Title:

Perchlorate in the feed-dairy continuum of the southwestern United States.

Abstract Source:

J Agric Food Chem. 2008 Jul 9;56(13):5443-50. Epub 2008 Jun 13. PMID: 18553887

Abstract Author(s):

C A Sanchez, B C Blount, L Valentin-Blasini, S M Lesch, R I Krieger

Article Affiliation:

Department of Soil, Water, and Environmental Sciences, Yuma Agricultural Center, The University of Arizona, Yuma, Arizona 85364, USA.


Perchlorate has the potential to cause thyroid dysfunction by inhibiting iodide uptake by the sodium iodide symporter. Perchlorate-contaminated waters may lead to human exposure through drinking water and food chain transfer in crops by way of irrigation water. Perchlorate has been found in dairy milk collected nationally and internationally. This study was conducted to evaluate perchlorate in the feed-dairy continuum in the southwestern United States. All feed products collected at dairies in this study had detectable levels of perchlorate as analyzed by ion chromatography-tandem mass spectrometry. The calculated total perchlorate intake across dairies ranged from 1.9 to 12.7 mg/cow per day. The variation in total perchlorate intake across dairies was largely associated with variation in forage and silage products. Alfalfa products were the single most important source of perchlorate intake variability among dairies. The estimated perchlorate intake from drinking water ranged from 0.01 mg per cow per day and was generally less than 2% of the total perchlorate intake. The perchlorate content of milk ranged from 0.9 to 10.3 microg/L and was similar to levels reported by the Food and Drug Administration's Total Diet Study. The perchlorate content of milk was significantly related to the presence of perchlorate in feed but the variation of perchlorate in milk could not be explained by feed intake alone.

Study Type : Animal Study
Additional Links
Problem Substances : Perchlorate : CK(142) : AC(33)
Adverse Pharmacological Actions : Bioaccumulator : CK(115) : AC(32)

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