Abstract Title:

Physiologic calcification of the pineal gland in children on computed tomography: prevalence, observer reliability and association with choroid plexus calcification.

Abstract Source:

Acad Radiol. 2006 Jul;13(7):822-6. PMID: 16777555

Abstract Author(s):

Anthony James Doyle, Graeme D Anderson

Article Affiliation:

Department of Radiology, Middlemore Hospital, University of Auckland, Hospital Road, Otahuhu, Auckland 1006, New Zealand. [email protected]


RATIONALE AND OBJECTIVES: To evaluate the prevalence of physiologic pineal calcification, estimate observer variability, and examine the association with choroid plexus calcification.

MATERIALS AND METHODS: A retrospective review of hard copy head computed tomography films of 242 patients age younger than 16 years by two independent observers.

RESULTS: Physiologic pineal calcification was present in 20% of the whole group, in 39% of those 8-14 years age, in 8% of those younger than 10 years age, and in 1% of those younger than age 6 years. Observer agreement was very good (kappa = 0.72). Choroid plexus calcification was present in 16% and was four times as common in those with pineal calcification (38% versus 10%, P = .005), with very good observer agreement (kappa = 0.74).

CONCLUSION: Physiologic pineal calcification is more common in children than previously reported, mostly because of improving computed tomography technology. There is an association with choroid plexus calcification.

Study Type : Human Study

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