Abstract Title:

Phytochemical analysis of Gymnema sylvestre and evaluation of its antimicrobial activity.

Abstract Source:

Nat Prod Res. 2013 ;27(6):583-7. Epub 2012 Apr 3. PMID: 22468693

Abstract Author(s):

Bhuvaneswari Chodisetti, Kiranmayee Rao, Archana Giri

Article Affiliation:

Bhuvaneswari Chodisetti


Gymnema sylvestre (CS 149), known to be a rich source of saponins and other valuable phytochemicals, has been analysed for antimicrobial activity. The chloroform extracts of aerial and root parts of G. sylvestre exhibited higher antimicrobial activity as compared to diethyl ether and acetone. The root extracts of chloroform have shown competitive minimum inhibitory concentration and minimum bactericidal concentration values in the range of 0.04-1.28 mg mL(-1) and 0.08-2.56 mg/mL, respectively, towards the pathogens. The GC-MS analysis of chloroform extracts has shown the presence of compounds like eicosane, oleic acid, stigmasterol and vitamin E.

Study Type : In Vitro Study

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