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Abstract Title:

Phytochemical constituents, antimicrobial and antioxidant activities of Kumaun Himalayan Hoop Pine bark extract.

Abstract Source:

Nat Prod Res. 2020 Nov 29:1-5. Epub 2020 Nov 29. PMID: 33251860

Abstract Author(s):

Parikshit Kumar, S C Sati, Kapil Khulbe, Prabha Pant, Amrendra Nath Tripathi, Kunwar Sarvendra

Article Affiliation:

Parikshit Kumar

Abstract:

The chemical composition of the methanol extract obtained fromSweet. bark was determined by GC-MS analysis with its antioxidant and antibacterial potential, for the first time. A total of 73 compounds were identified and the extract was strongly characterised by Viridiflorene; Androstan-17-one, 3-ethyl-3-hydroxy-, (5α)-; 8-Isopropenyl-1,3,3,7-tetramethyl-bicyclo[5.1.0]oct-5-en-2-one; 3,6,9-Triethyl-3,6,9-trimethyl-tetracyclo[6.1.0.0 ∼ 2,4∼.0 ∼ 5,7∼]-nonane; Longifolenaldehyde; (-)-Caryophyllen-(I1); 2-hydroxymethyl-5-furfural; Methyl commate B; 3-Ethyl-3-hydroxyandrostan-17-one; 3-Hydroxybenzoic acid as the main components (55.39%).extract presents IC, 53.52 µg/mL and 65.29 µg/mL using DPPH and HOscavenging assay, respectively. The antibacterial activity of the extract was evaluated for eight microorganisms showed that the extract had a remarkable inhibitory potential with a mean zone diameter of inhibition ranging from 09 to 21 mm. The methanol extract ofshowed significant antibacterial activity against(21 mm, ZOI) with MIC and MBC values 15.6 and 31.25 µg/mL, respectively.

Study Type : In Vitro Study

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