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Article Publish Status: FREE
Abstract Title:

Plant-derived nootropics and human cognition: A systematic review.

Abstract Source:

Crit Rev Food Sci Nutr. 2022 Jan 3:1-25. Epub 2022 Jan 3. PMID: 34978226

Abstract Author(s):

Cristina Lorca, María Mulet, Catalina Arévalo-Caro, MÁngeles Sanchez, Ainhoa Perez, María Perrino, Anna Bach-Faig, Alicia Aguilar-Martínez, Elisabet Vilella, Xavier Gallart-Palau, Aida Serra

Article Affiliation:

Cristina Lorca

Abstract:

Substances with modulatory capabilities on certain aspects of human cognition have been revered as nootropics from the dawn of time. The plant kingdom provides most of the currently available nootropics of natural origin. Here, in this systematic review, we aim to provide state-of-the-art information regarding proven and unproven effects of plant-derived nootropics (PDNs) on human cognition in conditions of health and disease. Six independent searches, one for each neurocognitive domain (NCD), were performed in parallel using three independent scientific library databases: PubMed, Cochrane and Scopus. Only scientific studies and systematic reviews with humans published between January 2000 and November 2021 were reviewed, and 256 papers were included.was the most relevant nootropic regarding perceptual and motor functions.improves language, learning and memory.(Ashwagandha) modulates anxiety and social-related cognitions. Caffeine enhances attention and executive functions. Together, the results from the compiled studies highlight the nootropic effects and the inconsistencies regarding PDNs that require further research.Supplemental data for this article is available online at https://doi.org/10.1080/10408398.2021.2021137.

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