Article Publish Status: FREE
Abstract Title:

Plasma Vitamin D Deficiency Is Associated With Poor Sleep Quality and Night-Time Eating at Mid-Pregnancy in Singapore.

Abstract Source:

Nutrients. 2017 Mar 29 ;9(4). Epub 2017 Mar 29. PMID: 28353643

Abstract Author(s):

Tuck Seng Cheng, See Ling Loy, Yin Bun Cheung, Shirong Cai, Marjorelee T Colega, Keith M Godfrey, Yap-Seng Chong, Kok Hian Tan, Lynette Pei-Chi Shek, Yung Seng Lee, Ngee Lek, Jerry Kok Yen Chan, Mary Foong-Fong Chong, Fabian Yap

Article Affiliation:

Tuck Seng Cheng


Plasma 25-hydroxyvitamin D (25OHD) deficiency, poor sleep quality, and night-time eating, have been independently associated with adverse pregnancy outcomes, but their inter-relationships are yet to be evaluated. We aimed to investigate the associations between maternal plasma 25OHD status and sleep quality and circadian eating patterns during pregnancy. Data on pregnant women (= 890) from a prospective cohort (Growing Up in Singapore Towards healthy Outcomes) were analyzed. Plasma 25OHD concentration was measured, while the Pittsburgh sleep quality index (PSQI) and 24-h dietary recall were administered to women at 26-28 weeks' gestation. Plasma 25OHD status was defined as sufficient (>75 nmol/L), insufficient (50-75 nmol/L), or deficient (<50 nmol/L). Poor sleep quality was defined by a total global PSQI score>5. Predominantly day-time (pDT) and predominantly night-time (pNT) were defined according to consumption of greater proportion of calories (i.e.,>50%) from 07:00-18:59 and from 19:00-06:59, respectively. After adjustment for confounders, women with plasma 25OHD deficiency had higher odds of poor sleep quality (odds ratio (OR) 3.49; 95% confidence interval (CI) 1.84-6.63) and pNT eating (OR: 1.85; 95% CI 1.00-3.41) than those who were 25OHD sufficient. Our findings show the association of maternal plasma 25OHD deficiency with poor sleep quality and pNT eating at mid-pregnancy.

Study Type : Human Study

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